Since i wash him in flea shampoo and worm him with a tablet (not from the advocate brand) and he is perfectly fine! But a few vets have told me that it is not generally recommended for border collies as it can cause seizures and neurological problems. Thank you. also too try and put it on after the bath 48 hours. It may be they say to put it on in smaller doses but after reading all this I am going to ask for a different product for him. Thank you Cori for your added information. When reviewing clinical trial data, experts will focus on grade 3 or higher side effects. . He was only 1kg in weight and 14 weeks old, I am terrified I am going to loose him. How many dogs have to have these reactions before it is acknowledged? My chiweenie was given Advantage II and exhibited signs right away. My vet just told me to keep an eye on him. Oh, okay. She also appears to be reacting to the product: lethargic and sickness. we took our 8 week old Border Collie to the vet and paid for a package called “the best start” as part of this package the vet applied Advocate but did not consult with us about it she simply put it on the pups neck. I feel it was the Advocate that caused this. Around may last year when our BC was a year old he went to bite someone who bent down beside him to get into their bag. He’s now treated with bd Epiphen 60. I am also disheartened that we are advised by our vets to put our pets onto these regular plans and annual vaccinations to ‘protect’ them and they are doing quite the opposite. Bayer Advocate for dogs is a once-monthly topical treatment. We have stressed over why a young, healthy dog can suddenly get this disease. Emergency vets are also pretty open to these types of reactions because they have seen them before. he is now suffering and the vets have no idea whats wrong with him. As the months went on his reactions became progressively worse to the point my husband had to hold him in a corner while I put it on his neck. Any ideas anyone. He regained use of legs but is still unsteady and cannot do basic stuff such as cocking his leg, scratching or jumping into car boot etc. There have been a handful of accounts of the virus turning up in cerebrospinal fluid, raising the possibility that SARS-CoV-2, the virus that causes COVID-19, may be able to directly infect brain cells. Since her first application of advocate on Monday she has been very poorly. But no more Advocate and will being making sure that anything she does have does not contain Ivermectin. very worried about her. Now, there are more than 300 studies from around the world that have documented "neurological abnormalities" in COVID-19 patients, ranging from mild symptoms—like headaches, anosmia (the loss of taste and smell), and tingling in extremities—to extreme cases—including aphasia (losing the ability to speak), seizures, and strokes. She suddenly had spasms in her back legs, an arched back and shaking. Has your dog recovered? My 21 month old working cocker spaniel had Domodex mites when he was a young puppy. This allows for a potential for money savings and also less stress for the dog and owner. Here is Bayer’s contact page https://www.bayer.com/en/contact.aspx, Best Regards, letting you all know that anyone with I sure hope all the above pups are doing well. Then she had another in February and may. The neurological side effects from advocate, does this include siezures? He hasn’t done this for years!!!! I spend 5 hours a day trying to encourage him to eat, I am totally exhausted, he now barley eats less than a quarter of his food. When I checked on him the sight was horrifying. Try & wash it off the area you applied it that’s what I did hope little ones ok x, My 2 & half year old Staff was given this as he has a pinkish skin underneath & the vet said it was better than frontline s guards against mange that he could pick up from foxes . The only time you would not use all is maybe if your dog is at the low end of that weight range. In addition to heartworm prevention and also flea and lice treatment and infestation prevention, Advocate can also prevent and treat other parasites. is using advocate for demodectic mange iand their dog is having a reaction it may be worth trying aludex wash Marie. reason puppy was taken to vets ( hes 8 months old) is he couldnt get up, whne he did he fell back down as if legs gave way. They so wrong my dog now very ill. Hi Katherine, I don’t know how old this post is but my 7 month old dog is experiencing the same symptoms. "He has to be compensated for his sufferings. Also, please share your story on twitter with #afteradvantage and #bayer hashtags. Our dog is heartworm positive, and because of that she cannot use ivermectin. Speckles will be sending good vibes! • Some other side effects may occur such as fever, chills, fatigue, feeling of discomfort, headache, joint pain, muscle pain and nausea. I made the decision to look online for clues to his behaviour and came across a website about advocate and adverse reactions in BC with a build up of toxins in a dogs brain who had a certain gene deficiency. Can’t walk straight and keep on crying. We were prescribed Advocate for our 18 month old Cavachon, as he refuses to take pills. He never cries or whimpers but has been doing so all day. What are the risks associated with Advocate? So brutal. We are now even more upset thinking that we may have caused her downfall and cannot come to terms with it, surely this problem should be more widely known, and certainly by vets. They seem a little too quick for profit to do the appropriate testing and disclosure. advocate (2nd), we noticed changed in his behavior, very fearful and anxious. I noticed it after 4 days of advocate treatment. Needless to say she said there were no problems associated with the use of Advocate. Since your friend’s dog seems to have had a neurological reaction, I’m not sure this would help, but it might. I do not know the effects of these ingredients on herding breeds. Which I have been. (For more on the possible disease processes involved in these neurological complications, see Multiple disease processes below. The next month the same thing happened so I bathed him and didn’t re-apply more until his back cleared up then started again and the same thing happened so I got in touch with the company I purchased it from who assured me it was the genuine product so I again bathed him and waited for it to clear. After the first siezure she was taken to the vet but he had no answer to what may have caused this! Our vet had previously prescibed painkiller Carprieve & Ronaxan 100mg antibiotics for a sore split paw.This delayed the flea treatment for a couple of months. Vet said they will speak to Advocate and seek their advice. I work in a homeopathic clinic, for humans not veterinary and one of our patients came in and said their dog had collapsed after going outside after they had sprayed insecticide – I know it isn’t exactly the same but it doesn’t matter from homeopathic point of view. She did a day later and said she had spoken to the manufacturer who said that these claims were unfounded at the explanation for my dog was behavioural. Please contact me if your dog had a reaction to Advocate or Advantage Multi. I am so sorry to hear about your little dog, i wish you all well and that she is better soon……i will never use this product again! Speak up and ask questions to make sure your loved one gets the best possible rehabilitation and care. Hi,my dog too had same reaction Sunday morning on advocate,back legs kept going,swaying all over the place,never again.x, We have just had a similar experience after using Advocate. I’m very worried after reading these blogs as he’s so tiny and young. “But these haven’t yet been studied specifically in COVID-19 patients,” he says. I have tried all three Bayer solutions and all are effective: Advantage (and advantage multi) , Advocate and Advantix; the latter I would only bother using in bad mosquito areas and make sure it is nowhere near cats. Our Homeopath gave them something for their dog, based on the symptoms. He isn’t walking properly, is very unbalanced and sounds the same as some of these dogs on here. Such complications are thought to be related both to severe illness and to intensive care treatment. I had all the tests run on Speckles – MRI, X-ray, Genetics, etc. Speak up. Please get in touch with me as I am very concerned that it is Advantage that has caused this. He did not want any food at all and was very lethargic. She has therefore NOT had the sickness( she couldnt even keep a drop of However, as many have commented here, make sure you are okay with using this product on your dog because there have been some bad reactions to using this product. We can’t even turn over in bed on a night without him running him from the landing growing and Barking. “The two most common neurological problems seem to be stroke and delirium.”. Thank you. the demodex on my dog ears came back. Should I use pancure instead? She has just had another today, I used advocate on her 2 days ago and the last time she had a seizure it was a few days after treating her with advocate. After taking him to queen mother Vetinary hospital and them watching his recorded episodes they are pretty Sure he has a ‘movement disorder’ which is apparently minor and not much can be done. He is a Lhasa/Poodle cross. She is now 6 months, and she suffered a siezure once last week and has had another one this week! It is important to make sure that the right product is used, the FDA said. A human papillomavirus vaccine may trigger fatal autoimmune or neurological events in some cases, ... UBC researchers advocate HPV vaccine scrutiny. At this point I contacted Bayers directly. Q. I took him straight there and he was taken away for tests. I’m so sorry everyone is having reactions with your pets…now I’m paranoid LOL gonna watch mine closer after application ! Advocate is a liquid and you have to put it on the skin of the dog for it to be effective. My lovely 9 month lab/collie cross has been diagnosed today with SR meningitis. So . Hi I’ve just read some of your remarks. This site uses Akismet to reduce spam. He needs steroids and has had MRI, lumbar puncture and bloods. I will never use advocate on him ever again. My dog also had this type of reaction to Advantage Multi (lost use of back legs, neurological symptoms etc). 76, No. … everything seems fine in the first 3 weeks. I know these dogs have symptoms. It took three days for her to return to normal. Please can someone advise me of a proven and safe alternative to Advocate to prevent Lungworm. the vet asked if anything had been different for him before the seizures, of course we racked our brains as to what it may be, then I remembered treating him with Advocate 5 days before. I think some pups are just more prone to a reoccurrence. My vet has seen this reaction before. I have a 4yr old Westie, I have been giving him advocate for 3 years. Michelle 7 days after we administered the spot on the following happened. But taking this medication is the only thing the owner can think of. What these pharmaceuticals are doing is criminal. Lost control of back legs. It effects more than herding dogs as we experienced yesterday with our 6 year old yorkie. Could it be the advocate toxins are still built up in his brain or that they did their damage already? It just depends on each individual dog and their unique situation. His temperature has been too high for a week, he has excessive mucus or saliva in his throat and is drowsy, unresponsive, shaky and depressed – doesn’t seem to know or recognise anyone – even me. Been giving this to my dog chihuahua for 2 years n dog has developed liver bile problem am not sure if it’s this but dog has been very sick bloods shower liver problem n I wonder if this drug is toxic for her liver. She has had Advocate since she was a puppy and thinking back may have suffered more minor symptoms before after using it. In some patients, COVID-19 seems to trigger a runaway immune response that can cause problems throughout the body. nothing else had worked It is Side effects (also called adverse events) are measured in grades 1-4 with 4 being the most severe. I can not think of anything else as everything she has had today she’s had before It was very worrying. My dog, a Greek Hound mix, has been having this product every month for the past 4 years, as he does eat anything and everything outside. I hope you find some answers that help him. Thanks for visiting our blog. Best wishes for your dog. I spoke to the vet who said that this was perfectly normal!!!! I read that Advocate should never be given to Collie dogs! Plus she was a border collie. and I am using the aludex wash to clear the mange up. He has suffered what we thought was arthiritis for years now, and last year he was on pain killers (big brown tablets that taste good for dogs) in the hope this would help him to walk better (got very stiff if walking for too long – i.e more than 20 mins) – he developed a terrible allergy, took ages to work out it was the pain-killers, vets thought it was unlikely. important than whether or not an We took her to the vet and mentioned the Advocate the vet said usually only side effects would be a rash/itching at the site.She told us to bring her back next day she saw another vet and was kept in while they ran blood tests, these came back negative so we were told to take her to a large Vet company for a scan.The vets and she saw at least 4 there kept her in for a day ran more tests and decided to treat a brain disorder. After a false diagnosis and treatment of a vaginal infection, her condition became worse. This cant happen to anyone else. Advocate for Dogs (also sold as “Advantage Multi” and both manufactured by Bayer) is a topical product that is designed to prevent heartworms, fleas and other internal and external parasitic infestations in dogs. I decided to start a diary to see if I could link it to any particular thing. I SAT IN FRONT OF MY DEAR PET FOR 4 HOURS CONTINUOUSLY AFTER APPLICATION. Looking at packaging on the web, it doesn’t state these effects either, so its the manufacturers fault. Surely the Vets should make people more aware of the side effects. I am devestated, my darling pet seems back to normal now but I will NEVER EVER give him this poison again. My dog won’t be getting this product again and I hope he has no further systems. No animal should have to suffer like these dogs have. Yes neurological adverse reactions! Hes been in now for 4 days. Two vets have said vestibular disease (like a stroke) or worse like a brain tumor. All so unnecessary , will never use again. You could contact the manufacturer for their advice: https://www.bayer.com/en/contact.aspx. He sat in the kitchen for an hour and a half just staring into space. As he was 11kg in weight the vet gave him 11-25kg pipettes, I think this was way too much As he is still a small dog and he had also been recently cut and groomed his fur was shorter so it absorbed quicker, hence causing this skin reaction. Not sure I should be using again, although do not want her picking up some of these diseases that the foxes carry including mange. in the meantime what we can do to alleviate his muscle spasms ? “Trials of antivirals and other therapies being tested to treat COVID-19 are looking at some very coarse outcome measures, like survival or duration of hospitalization. My vet seems to think this is allergy, but said could be allergy to anything, after reading some of these other people’s experiences, I am now thinking it’s the advocate !!!! Sorry about your dog ,get the vet to check for SRMA (steroid responsive meningitis ) it is quite common. They were extremely swift and professional and advised me to contact my vet to discuss alternative treatment. Advocate is legally clear by saying it does not eradicate rounds and hooks, just that it helps control. We stopped giving it to him for a few months but tried it again today. We just went to the vet and he was just given again vitamin B injection and pain reliever for his muscle spasms. 382, No. My dog was given Advocate as part of a monthly pet care plan sold to me by my vets. None of the dogs had serious or unpredictable medical conditions, and all lived between 14 – 16 years. I had to use the advocate monthly to keep demodectic mange at bay but I haven’t used the advocate for 7 And following each of those outbreaks, Stevens says, “there were reports of people suffering long-lasting neurological injuries.”, Neurology experts are concerned that COVID-19 could leave a similar legacy. My 9yr old pug is currently extremely lethargic and weak. I’m no vet but I think Pyrantel is an OTC one. Heartworm medicine for dogs that is in the form of a chewable pill such as Heartgard or Interceptor contains ingredients such as beef flavoring that some sensitive dogs may be allergic to. I’ve also found that a grain free salmon diet, helps the skin and coat as well as coconut oil applied after a bath. Hopefully your dog will be fine and not have any lasting problems since you washed it off and it has had time to get out of his system. 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