Water solubility Solubility in organic solvents / fat solubility Surface tension Flash point Auto flammability Flammability Explosiveness Oxidising properties Oxidation reduction potential Stability in organic solvents and identity of [4,9] Poly( Ethylene Disposal considerations Currently, SA is produced exclusively from alkaline pyrolysis of castor oil. Material Safety Data Sheet Sebacic acid sc-215843 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Sebacic acid STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. Compared with short-chain aliphatic acid, sebacic acid is more suitable for the preparation of polyesters, as short-chain aliphatic acids always conduce to intramolecular condensation. Sebacic Acid was named from the Latin sebaceus (tallow candle) or … It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. PubChem ChemSpider SMILES 3400 mg/kg (大鼠经口) [5] 6000 mg/kg (小鼠经口) [5] 若非注明，所有数据均出自一般条件（25 ，100 kPa）下。 To detect the synergistic effect, solubilities of sebacic acid in 14.35 %, 36.97 %, 79.81 %, and 90.00 % mole fraction ethanol aqueous solution were determined to supplement our previous report. 1272/2008 [CLP] Extra labelling to displayExtra classification(s) to display Sebacic acid is an intermediate product of ��- oxidation of long-chain aliphatic acids. Mobility Will likely be mobile in the environment due to its water solubility. We also Provide Trading Suppliers & Manufacture for 17265-14-4 SEBACIC ACID ��� Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Solubility in water: 0.25 g/L[1] 遺����援ъ“��� (HOOC)(CH2)8(COOH)��� ��댁�쇨린��곗�쇰�� ��쇳�댁�� ��곗��(���珥�瑜� 留���ㅻ�� 寃�)瑜� ��삵����� sebum������ ������������ sebacic acid濡� 紐�紐���������쇰ʼn �����댄��吏� ������ 寃���쇰�� �����ㅼ�� 遺�留���������대�� 誘몄�몃��吏���� 諛������������� ������. Sublimes slowly at 750 mm Hg when heated to melting point. Abstract. 5-Oxo-ODE is a structural analog of 5-oxo-eicosatetraenoic acid and like this oxo-eicosatetraenoic acid is an exceptionally potent activator of eosinophils, monocytes, and other pro-inflammatory cells from humans and other species. Contact Supplier High quality Sebacic Acid Disodium Salt Supplier The castor oil is treated with caustic soda at high temperature, for example 250 C, so that saponification, leading to the formation of ricinoleic acid, is followed by a reaction giving sebacic acid and octan-2-ol: Office : Sebacic India Limited 301 World Trade Center, Sayajigunj, Vadodara - 390 005. Other names. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. It is a conjugate acid of a sebacate (2-) and a sebacate. About Sebacic Acid Sebracic acid is a white powdered crystal that is resolved in ethanol and ether, and it possess low water solubility. Bioaccumulation/ AccumulationNo information available. Diesters of sebacic acid find various applications as plasticizers, solvents and lubricants. Sebacic Acid Safety Data Sheet According to Federal Register / Vol. Human neutrophils can convert sebacic acid to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid (5-oxo-ODE). Sebacic acid is a normal urinary acid. Solubility Slightly soluble in water. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Decanedioic acid sodium salt TOP1 supplier Cas No: 17265-14-4 USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Sebacic Acid was named from the Latin sebaceus (tallow candle) or sebum (tallow) in reference to its use in the manufacture of candles. Lookchem Provide Cas No.17265-14-4 Basic information: Properties,Safety Data,Sds and Other Datebase. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid for synthesis. Safety Data Sheet (Sebacic Acid) DATE PREPARED: 1/20/2016 Page 6 of 6 Section 16. Mobility Will likely be mobile in the environment due to its water solubility. Display Name: Sebacic acid EC Number: 203-845-5 EC Name: Sebacic acid CAS Number: 111-20-6 Molecular formula: C10H18O4 IUPAC Name: decanedioic acid Property Value Probability; Human Intestinal Absorption + 0.5731: Blood Brain Barrier + 0.7397: Caco-2 permeable-0.6412: P-glycoprotein substrate In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. It is resolved in ethanol, ether and soluble slightly in water. Currently, SA is produced exclusively from alkaline pyrolysis of castor oil. CB-839(Telaglenastat) inudces autophagy and has antitumor activity. 77, No. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. Gujarat India. An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. Regd. SEBACIC ACID 1 Physical and Chemical Fuction: Molecular Formula: HOOC(CH2)8COOH Molecular Weight: 202.25 It is white powder crystal, slightly dissolves in water, completely dissolved in ethanol or ether, but not in benzene. Sebacic acid Description In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. Sebacic acid (8Cl) Registration dossier . and has antitumor activity. It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). Sebacic acid is a derivative of castor oil. It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. Sebazinsaeure. SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. It is a white flake or powdered solid. [6], InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), InChI=1/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), Except where otherwise noted, data are given for materials in their, Ullmann's Encyclopedia of Industrial Chemistry, "Mammalian Wax Biosynthesis II: Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family", https://en.wikipedia.org/w/index.php?title=Sebacic_acid&oldid=999055436, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, 131 to 134.5 °C (267.8 to 274.1 °F; 404.1 to 407.6 K), This page was last edited on 8 January 2021, at 07:53. C(CCCCC(=O)O)CCCC(=O)O Sebacic acid: ��ε�� ��������� 1,8 ... Foti, C.; Sammartano, S. Solubility and Activity Coefficients of Acidic and Basic Nonelectrolytes in Aqueous Salt Solutions. It is a white flake or powdered solid. CopyCopied, InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14) Sebacic acid (8CI) Registration dossier . 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes. Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. 2. SEBACIC ACID: ICSC: 1685: 1,10-Decanedioic acid 1,8-Octanedicarboxylic acid Decanedioic acid: April 2008 Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. Herein, we present an e Component log Pow Decanedioic acid 1.5 13. Degree of solubility in water: 1 g/l 20 °C: Solubility (very soluble in) Alcohol: 111-20-6. Sebacic acid for synthesis. Sebacic acid is produced from castor oil by cleavage of ricinoleic acid, which is obtained from castor oil. Registrant / Supplier Registered Updated 3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium 2016 [Confidential] ARKEMA CASDA 420 rue d'Estienne d'Orves 92700 Colombes France 2010 ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France Octanol is a byproduct. PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. Solubility results of sebacic acid were observed to be highly correlated with quadratic model according to analysis of variance. Sigma-Aldrich offers a number of Sebacic acid products. CopyCopied, CXMXRPHRNRROMY-UHFFFAOYSA-N Approximation models were employed for determining solubility of sebacic acid at elevated temperatures. - Find MSDS or SDS, a COA, data sheets and more information. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. The solubility in 95% ethanol (100ml) is 11.7g. Sebacic acid (SA) is an aliphatic ten-carbon dicarboxylic acid (1,10-decanedioic acid) with a variety of industrial applications, including the production of plasticizers, lubricants, cosmetics, and plastics. [2], It can also be obtained from decalin via the tertiary hydroperoxide, which gives cyclodecenone, a precursor to sebacic acid. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. : Rinse cautiously with water for several minutes. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. Solubility Show More Product # Description 283258 Sebacic acid, 99%, 84809 Sebacic acid, ≥95.0% (GC), 8.00753 Sebacic acid, for synthesis, Sorry we cannot compare more than 4 products at a time. It is resolved in ethanol, ether and soluble slightly in water. Sebacic acid is a derivative of castor oil. Combustible. 2. Sebacic Acid PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. Solubilities of sebacic acid in binary ethanol + water solvent mixtures were measured by the dynamic method using a laser monitoring observation technique at a … May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Other Information Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes.Remove contact lenses, if present and - Find MSDS or SDS, a COA, data sheets and more information. Slightly soluble in water. Incompatible with strong oxidizingagents, bases, reducing agents. The product is described as non-hazardous, though in its powdered form it can be prone to flash ignition (a typical risk in handling fine organic powders). Registration dossier . Sebacic Acid. Label elements Labelling according to Regulation (EC) No. Sebacic acid: Overview. SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. Sebacic acid is a normal urinary acid. View information & documentation regarding Sebacic acid, including CAS, MSDS & more. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Sebacic acid is a derivative of castor oil. text.skipToContent text.skipToNavigation. Response surface methodology was used to study the combined effects of the different parameters such as temperature, static and dynamic time to optimize the process conditions for the maximum solubility of sebacic acid. Catalogue Number Availability Packaging Qty/Pack Price SEBACIC ACID FOR SYNTHESIS Safety Data Sheet www.lobachemie.com 09/04/2015 2/8 Adverse physicochemical, human health and environmental effects No additional information available 2.2. Telaglenastat (CB-839) New Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. �����щ�� ��ъ�⑹����� 留�寃� ��ъ�댄�몃�� ��ㅼ�������� ��ъ�⑹��媛� ��ъ�댄�몃�쇰낫��� ���������寃� ��댁�⑺�� ��� ������濡� 荑���ㅻ�� ��ъ�⑺�⑸�����. It is a white flake or powdered solid. DESCRIPTION & APPLICATIONS Sebacic Acid is a white flake or powdered crystal. Sebacic acid is a dicarboxylic acid with structure (CH 2) 8 (COOH), and is naturally occurring. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. 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Register / Vol aliphatic acids 610, plasticizers, lubricants, hydraulic fluids cosmetics., properties, spectra, suppliers and links for: sebacic acid an. 100Ml ) is 11.7g cosmetics and candles a soluble salt urinary acid - Find MSDS or,. Soluble salt water solubility works on polyesters of sebacic acid is normally made from castor oil. 2... Sebaceus is Latin for tallow, and it possess low water solubility and! Environmental effects No additional information available 2.2 ethanol and ether, and refers to its use in manufacture. And hexamethylene diisocyanate react through condensation polymerization to produce nylon 6-10 oil is treated with caustic soda high. To its water solubility acid are rare both organic and inorganic inudces autophagy and has activity. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization a... 301 World Trade Center, Sayajigunj, Vadodara - 390 005 % ethanol ( 100ml ) 11.7g. 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