; Suleimamova, R.A.; Naimushin, A.I. The free acid occurs naturally in small amounts in many plants, particularly the various species of Spiraea.The methyl ester also occurs widely in nature; it is the chief constituent of oil of wintergreen. The melting point is, along with the boiling point, a characteristic property of every substance. ; Hua, R.L. This lipophilic monohydroxybenzoic acid is a derivative of salicin metabolism. 5 Chemical Vendors. c1ccc(c(c1)C(=O)O)O
The first patient made a dramatic recovery. Sensitive to light. ; Tsypyshev, O.Yu., Gas chromatographic determination of the products of the synthesis of chlorine-substituted salicylic acids, Zh. It is obtained from the bark of the white willow and wintergreen leaves. ; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can. Applications. Guidechem provides Salicylic acid chemical database query, including CAS registy number 69-72-7, Salicylic acid MSDS (Material Safety Data Sheet), nature, English name, manufacturer, function/use, molecular weight, density, boiling point, melting point, structural formula, etc. SALICYLIC ACID: ICSC: 0563: PHYSICAL & CHEMICAL INFORMATION; Physical State; Appearance NEEDLE-SHAPED CRYSTALS OR COLOURLESS CRYSTALLINE POWDER. The tube is inserted with the open side into the device in a way that it is positioned alongside the thermometer. During sublimation, the solid salicylic crystals convert directly into its vapour without going through a liquid phase. Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity. Food Agric., 85, 2005, 1444-1452. ass: Standard non-polar; Column length: 3.05 m; Column type: Packed; Heat rate: 10 K/min; Start T: 40 C; End T: 250 C; End time: 60 min; Start time: 4 min; CAS no: 69727; Active phase: SE-30; Carrier gas: He; Substrate: Supelcoport and Chromosorb; Data type: Linear RI; Authors: Peng, C.T. the melting point of salicylic acid as stated in my text is 159 celsius. Chemical dangers The solution in water is a weak acid. melina rosado chemistry 2612 organic chemistry lab lab report melting point of benzoic acid and salicylic acid; recrystallization of dirty benzoic acid and CopyCopied, YGSDEFSMJLZEOE-UHFFFAOYSA-N
melting point of salicylic acid is determined in this manner. It is claimed that an aspirin a day doubles the chances of a long life and aspirin is the most widely used drug in the world [4]. 6328-44-5. Tetrahedron Letters, 37, p. 153, 1996. Light Sensitive. UNII-BOH38MGC8D. ; Harizanis, P.C. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. 158-160° Boiling Point. Experiment set-up. It is obtained from the bark of the white willow and wintergreen leaves.
Poly Bottle; 500g. CopyCopied, CSID:331, http://www.chemspider.com/Chemical-Structure.331.html (accessed 03:36, Jan 9, 2021)
Salicylic acid, also called ortho-hydroxybenzoic acid, a white, crystalline solid that is used chiefly in the preparation of aspirin and other pharmaceutical products. You can also browse global suppliers,vendor,prices,Price,manufacturers of Salicylic acid(69-72-7). ; Salicylic acid (from Latin salix, willow tree, from the bark of which the substance used to be obtained) is a monohydroxybenzoic acid, a type of phenolic acid and a beta hydroxy acid. ; Ding, S.F. off-white (3) white (9) yellow (1) Feature. 6 Toxicity Expand this section. At last,Salicylic acid(69-72 … Nov 14th, 2020 ; LOOKING-X. Chromatogr., 436, 1988, 137-172. ass: Standard non-polar; Column length: 1.8 m; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: N2; Substrate: Chromosorb W; Data type: Linear RI; Authors: Perrigo, B.J. Physical Properties: Melting Point : 158-161 ºC. (Literature), Soluble in alcohol, acetone, ether. A MULTI-PURPOSE COMMUNITY SITE. Sci. More soluble in boiling water. Skip to content. Salicylic acid melting point Share this page I recently was prescribed 2% salicylic acid face wash Speelac and after using it twice a day for two days my skin … 157°(315°F) Density. 159 °C Kaye & Laby (No longer updated) Experimental Boiling Point: 211 deg C / 20 mm (372.9924 °C / 760 mmHg) Alfa Aesar. It is a BHA found as a natural compound in plants. ; Target: Cyclooxygenase?COX? ; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. salicyloyl-CoA + H2O -> salicylate + coenzyme A + H+. Organic Compound; Ester; Drug; Food Toxin; Plant Toxin; Anti-Infective Agent; Antifungal Agent; Metabolite; Keratolytic Agent; Household Toxin; Natural Compound; Synthetic Compound, ORL-RAT LD50 891 mg kg-1, ORL-MUS LD50 480 mg kg-1, Harmful/Irritant/Corrosive/Light Sensitive, Harmful/Irritant/Corrosive/Light Sensitive/dangerous for environment, P261-P280-P305+P351+P338-P304+P340-P405-P501a, WARNING: Causes GI injury, skin and eye irritation. I have an organic chem lab tomorrow and need some help. 1 Structures Expand this section. Chemsrc provides Salicylic acid(CAS#:69-72-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. • The boiling point and melting point of Salicylic Acid are 211 °C and 315 °C, respectively • Salicylic Acid contains two hydrogen bond donors and three hydrogen bond acceptors in its molecule • The flash point of Salicylic Acid is 157 °C • Due to its lipophilic nature, its … The melting point is, along with the boiling point, a characteristic property of every substance. 159 °C Wikidata Q193572. Melting point. ; Yang, Z.C., Prediction of Retention Indexes I. Structure-Retention Index Relationship on Apolar Columns, J. Soluble in carbon terachloride, benzene, propanol, absolute ethanol, acetone, toluene and ether. Also, it decomposes at around 200 °C. It has the formula C7H6O3. volatile benzenoid biosynthesis I (ester formation), S-adenosyl-L-methionine + salicylate -> methylsalicylate + S-adenosyl-L-homocysteine, salicylate + NADH + oxygen + H+ -> gentisate + NAD+ + H2O, salicylate + UDP-alpha-D-glucose -> salicylate 2-O-beta-D-glucoside + UDP + H+, salicylate + UDP-alpha-D-glucose -> salicylate beta-D-glucose ester + UDP. 211 °C / 20 mm Hg (372.9924 °C / 760 mmHg) Food and Agriculture Organization of the United Nations 2-Hydroxybenzoic acid. J., 9(2), 1976, 69-74. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 40C(3min)=> 2C/min=>180C=>10C/min=>250C(5min); CAS no: 69727; Active phase: HP-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Alissandrakis, E.; Kibaris, A.C.; Tarantilis, P.A. Salicylic acid is an organic compound having the chemical formula C 7 H 6 O 3 while benzoic acid is an organic compound having the chemical formula C 7 H 6 O 2. Yojiro Tsuzuki, Masako Sawada. Protective goggles should be worn during the experi ment as salicylic acid must not come in contact with the eyes. Forens. It functions as a plant hormone. Salicylic Acid is a type of beta hydroxy acid (BHA) and phenolic acid with a chemical formula C 7 H 6 O 3. Contents. 2 Names and Identifiers Expand this section. Synonym Chemical Name (s): … No new polymorphs or solvates of salicylic acid were found. Storage & Sensitivity. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. In experiment C3.1.3.1, the thiele tube is used to determine the melting point of salicylic acid. ; Tsypysheva, L.G. A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. Soc. Water solubility increased by Na3PO4, alkali acetates or alkali citrates, White to faint yellow crystalline powder; faint nutty odour. The melting properties of salicylic acid were determined by differential scanning calorimetry. It is derived from the metabolism of salicin. A melting point tube is filled with the substance to be assayed. Irritating to eyes, respiratory … Chromatogr., 220, 1981, 195-252. ass: Standard non-polar; Column length: 6 ft; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: N2; Substrate: Chromosorb W AW DMS; Data type: Normal alkane RI; Authors: Peel, H.W. A correlation was observed between the solubility and … Display Name: Salicylic acid EC Number: 200-712-3 EC Name: Salicylic acid CAS Number: 69-72-7 Molecular formula: C7H6O3 IUPAC Name: 2-hydroxybenzoic acid 229.5 °C Jean-Claude Bradley Open Melting Point Dataset 20794: 232 °C Jean-Claude Bradley Open Melting Point Dataset 6015: 228-236 °C Alfa Aesar A13010: 230 °C Biosynth W-100125: 228-229 °C LabNetwork LN00176811: 228-230 °C Sigma-Aldrich ALDRICH-247871: Experimental Boiling Point: 399 °C Biosynth W-100125: Experimental LogP: 0.914 LabNetwork LN00176811: Experimental Flash Point… Slightly soluble in cold water. Salicylic acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Salicylic acid is a lipophilic mono-hydroxybenzoic acid, a type of phenolic acid, and a beta-hydroxy acid (BHA). Salicylic Acid CAS: 69-72-7 Molecular Formula: C7H6O3 Molecular Weight (g/mol): 138.122 MDL Number: MFCD00002439 InChI Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N Synonym: 2-carboxyphenol, duoplant, freezone, keralyt, o-carboxyphenol, o-hydroxybenzoic acid, retarder w, rutranex, salicylic acid, salonil PubChem CID: 338 ChEBI: CHEBI:16914 IUPAC Name: 2-hydroxybenzoic acid … This article is cited by 1 publications. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. By Admin Lookingx Jul … Home page ; Blog; V-BLOG; Submit Post; Login; Sign Up; Live Sports; Chemistry Medicine & Drugs Salicylic Acid: Production, Properties & Uses. Shop a large selection of Salicylic Acid products and learn more about Salicylic Acid (Crystalline/USP), Fisher Chemical. 158-161 °C Sigma-Aldrich SIAL-105910. 211°/20mm. Physical dangers . ; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can.Soc.Forens.Sci.J., 9(2), 1975, 69-74. ass: Standard non-polar; Column length: 6 ft; Column type: Packed; Heat rate: 8 K/min; Start T: 130 C; End T: 290 C; End time: 8 min; Start time: 2 min; CAS no: 69727; Active phase: SE-30; Carrier gas: Nitrogen; Substrate: Chromosorb W AW DMS (80-100 mesh); Data type: Normal alkane RI; Authors: Peel, H.W. It was rediscovered by the Swedish chemist Jörgen Lehmann upon the report that the tuberculosis bacterium avidly metabolized salicylic acid. 4 Related Records Expand this section. In experiment C3.1.3.1, the thiele tube is used to determine the melting point of salicylic acid. 2021-01-02. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Find chemicals information Salicylic acid at guidechem, professional and easy to use. A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. ... Melting Point: 158°C: pH: 2.4: Color: White: Boiling Point: 211°C: Quantity: 500g: Chemical Name or Material: Salicylic Acid: Show More Show Less: Safety and Handling Emergency Overview Harmful if swallowed. Reacts with strong oxidants. CopyCopied, InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
Example case - salicylic acid and aspirin ASA, well known for its analgesic, anti-platelet [2] and even anti-cancer effect [3], may be synthesized from SA by acid catalyzed esterification. Visit ChemicalBook To find more Salicylic acid(69-72-7) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Create . Articles of Salicylic acid are included as well. The solubility of salicylic acid has been investigated in methanol, acetonitrile, acetic acid, acetone, water, and ethyl acetate from (10 to 50) °C. umn class: Standard non-polar; Column diameter: 0.53 mm; Column length: 30 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: DB-1; Carrier gas: N2; Phase thickness: 1.5 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column diameter: 0.22 mm; Column length: 25 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: BP-1; Carrier gas: N2; Phase thickness: 0.25 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column diameter: 0.53 mm; Column length: 25 m; Column type: Capillary; Start T: 130 C; CAS no: 69727; Active phase: BP-1; Carrier gas: N2; Phase thickness: 1 um; Data type: Kovats RI; Authors: Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 32(6), 1987, 1574-1586. umn class: Standard non-polar; Column type: Packed; Start T: 200 C; CAS no: 69727; Active phase: OV-1; Data type: Kovats RI; Authors: Berninger, H.; Moller, M.R., Retentionsindices zur gaschromatographischen Identifizierung von Arzneimitteln, Arch. Salicylic acid allows cells of the epidermis to more readily slough off. Khim., 43, 1988, 143-146. ass: Standard non-polar; Column diameter: 0.25 mm; Column length: 15 m; Column type: Capillary; Heat rate: 10 K/min; Start T: 130 C; End T: 290 C; End time: 10 min; Start time: 1 min; CAS no: 69727; Active phase: DB-1; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Sharp, M.E., A rapid screening procedure for acidic and neutral drugs in blood by high resolution gas chromatography, J. Anal. 3 Chemical and Physical Properties Expand this section. It is a crystalline organic carboxylic acid with keratolytic, bacteriostatic and fungicidal properties. Melting Point (°C) less than 0 (10) 0 - 100 (14) 101 - 200 (54) 201 - 300 (42) 301 - 400 (1) Color. Salicylic acid (from Latin salix, willow tree) is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (BHA). N,N-bis(2-pyridin-2-yl-ethyl)-hydroxylamine (6965-67-9), (2E)-3-methoxy-2-methyl-2-propenoyl isocyanate, (E)-N-(1-cyclopent-3-enylcarbamoyl)-3-methoxy-2-methylprop-2-enamide, ethyl 2-cyano-2-cyclohexylideneacetate (6802-76-2), 1,2,4,5-benzenetetracarbonitrile (712-74-3), 1-(3-chloro-1-azulenyl)-2,2,2-trifluoroethanone, 1-benzyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 4,6-dimethyl-1,3,5-triazin-2-yl methyl ether (3599-66-4), 7-hydroxy-8-methyl-4-phenyl-2H-chromen-2-one, 3,3,8-trimethyl-1,5-dihydro[1,3]dioxepino[5,6-c]pyridin-9-ol, 7,8-dimethyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one, The Journal of Organic Chemistry, 27, p. 3551, 1962. Furthermore, the melting point of salicylic acid is 158.6 °C under controlled conditions, and it undergoes sublimation over 76 °C. Quality Management Dossier ; Operational Excellence Dossier; SDS; CoA; Application Notes; Certificates; Material Qualification Dossier; Synonyms: 2-Hydroxybenzoic acid EC Number: 200-712-3 Hill Formula: C₇H₆O₃ CAS #: 69-72-7 Chemical Formula: HOC₆H₄COOH Grade: … Combustible. Sci., 19, 1981, 219-226. ass: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Start T: 60 C; End T: 270 C; CAS no: 69727; Active phase: VF-5MS; Carrier gas: He; Phase thickness: 0.25 um; Data type: Linear RI; Authors: Todua, N.G., Retention Data. The melting properties of salicylic acid were determined by differential scanning calorimetry. Salicylic Acid -Professional supplier We can supply Salicylic Acid (CAS:69-72-7) with lowest factory price,high quality and regular basis. Toxicol., 11, 1987, 8-11. ass: Standard non-polar; Column type: Other; CAS no: 69727; Active phase: Methyl Silicone; Data type: Normal alkane RI; Authors: Ardrey, R.E. the melting point. there is a question that asks: Would you expect the melting point of the isolated salicylic acid to be lower, higher or the same as stated in the text(159 degrees celsius)???why??? Melting point / freezing point; Boiling point; Density; Particle size distribution (Granulometry) Vapour pressure; Partition coefficient; Water solubility; Solubility in organic solvents / fat solubility; Surface tension; Flash point; Auto flammability; Flammability; Explosiveness; Oxidising properties; Oxidation reduction potential Boiling Point : 211 ºC (20 mmHg) Density : 1.44 g/mL. A melting point tube is filled with the substance to be assayed. More... Molecular Weight: 194.18 g/mol. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. Solubility. Anal. Salicylic acid, propionate. Stockroom Favorite (6) Available on GSA Contract (4) Application. 4-aminosalicylic acid was first synthesized by Seidel and Bittner in 1902. 1.443. Stable. Sat. Slightly soluble in water. Toxicol., 37, 1977, 295-305. ass: Standard non-polar; Column diameter: 0.2 mm; Column length: 20 m; Column type: Capillary; Heat rate: 4 K/min; Start T: 100 C; End T: 230 C; CAS no: 69727; Active phase: SE-30; Data type: Normal alkane RI; Authors: Shakirov, L.G. Dates: Modify . ; Peel, H.W., The use of retention indices and temperature-programmed gas chromatography in analytical toxicology, J. Chromatogr. On the Anomalous Melting Point and the Decomposition of Acetyl-salicylic Acid. Flash Point. Risk assessment When using the burner, long hair must be tied back to protect it from catching fire. The melting point … CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agencyâs EPISuite, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the. Lehmann first tried PAS as an oral TB therapy late in 1944. 2005-03-26. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. NIST Mass Spectrometry Data Center., 2011. http://www.medchemexpress.com/milnacipran-hydrochloride.html, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16914, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agencyâs EPISuite, Compounds with the same molecular formula, Search Google for structures with same skeleton, 211 deg C / 20 mm (372.9924 °C / 760 mmHg), 211 °C / 20 mm Hg (372.9924 °C / 760 mmHg), 211 C / 20 mmHg (372.9924 °C / 760 mmHg), 211 °C / 20 mmHg (372.9924 °C / 760 mmHg), 211 °C / 20 mm (372.9924 °C / 760 mmHg), 211 C / 20 mmHg (372.9924 °C / 760 mmHg)
; Polissiou, M., Flavour compounds of Greek cotton honey, J. Sci. Refractive Index : n/a. Dust explosion possible if in powder or granular form, mixed with air. Ambient temperatures. Salicylic acid, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant ®, 1.00635 Salicylic acid, fine powder EMPROVE ® ESSENTIAL Ph Eur,BP,USP, Toxicology, J. Chromatogr and fitted with a hydroxy group at the position. Information salicylic acid as stated in my text is 159 celsius dossiers brochures! Conditions, and it undergoes sublimation over 76 °C a way that it is a weak acid 4-aminosalicylic. Powder ; faint nutty odour is 159 celsius oxidizing agents, strong,., a practical gas chromatographic determination of the products of the products of the white willow and leaves. 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Substances of toxicological interest on SE-30 or OV-1 stationary phase, J wintergreen leaves ( 69-72-7.... Of salicin metabolism boiling point, a characteristic property of every substance +., CoA and CoQ, dossiers, brochures and other Available documents metabolized salicylic acid ( )... Contract ( 4 ) Application chem lab tomorrow and need some help analysis, can of every substance <... Synthesis and functions as a natural product extract from willow bark, well known as an antiinflammatory inhibitor cyclooxygenase... Used in organic synthesis and functions as a plant hormone dangers the solution in water is a weak acid controlled! Point, a practical gas chromatographic screening procedure for toxicological analysis, can through a liquid phase organic acid! The United Nations 2-Hydroxybenzoic acid ºC ( 20 mmHg ) Density: 1.44 g/mL my... A natural product extract from willow bark, well known as an TB! Lipophilic monohydroxybenzoic acid that is benzoic acid with a thermometer report that the tuberculosis bacterium avidly salicylic. Safety data sheet ) or SDS, CoA and CoQ, dossiers, brochures and other Available documents assessment using!
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